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Following back-to-back victories, there will be a temptation to name an unchanged starting XI for a third consecutive match.
Yet a trip to Liverpool means that Sam Allardyce could opt for a more defensive formation in his first derby in charge.
If the Toffees boss sticks with the 4-1-4-1 system, Aaron Lennon and Gylfi Sigurdsson could continue out wide, leaving Dominic Calvert-Lewin as the lone striker.
Oumar Niasse, Ademola Lookman and Nikola Vlasic provide attacking alternatives. Tom Davies and Wayne Rooney look set to continue in central midfield, leaving Idrissa Gueye in the defensive midfield role.
Morgan Schneiderlin does provide a strong alternative in the middle of the park should Allardyce look for greater defensive cover.
Two successive clean sheets mean the back four of Jonjoe Kenny, Mason Holgate, Ashley Williams and Cuco Martina may stay unchanged.
Michael Keane is a viable starter in central defence, however, and an option should the Everton manager consider using a three-man backline, while Phil Jagielka is also available again.
Leighton Baines, Seamus Coleman, Ramiro Funes Mori, James McCarthy and Ross Barkley all remain sidelined, as is Yannick Bolasie (lack of match fitness).