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Mauricio Pochettino has just two injury problems ahead of the Gameweek 28 trip to Chelsea. Dele Alli (hamstring) and Eric Dier (tonsilitis) are both ruled out for the encounter.
After returning to the side earlier than expected against Burnley, Harry Kane should lead the attack once again with Son Heung-min as his strike partner.
Christian Eriksen, Harry Winks and Moussa Sissoko look likely to hold down their places in the side while Erik Lamela and Lucas Moura will probably have to compete for the fourth midfielder position.
The defence is harder to predict with Pochettino quite fond of rotating at the back. Danny Rose’s 90-minute spell against Burnley could see him benched for Ben Davies, while Kieran Trippier should start at right-back after being reportedly rested at Turf Moor.
Davinson Sánchez was afforded similar treatment at the weekend, which would suggest Pochettino had in mind to start him at Stamford Bridge.
If there’s going to be a back-four for Spurs it would be between Jan Vertonghen and Toby Alderweireld for that final centre-back spot.