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A versatile player able to line up as a striker or on either flank, Clement claimed there is “a lot of interest” in his player.
“It is very likely that Dennis will leave,” he told La Dernière Heure. “He can also count on a lot of interest.
“It is the time for him to take a new step.”
Dennis, who has been capped twice by Nigeria, grabbed headlines last October when he scored twice against Real Madrid in the Champions League group stages.
He mimicked Cristiano Ronaldo’s celebration as he netted during the 2-2 draw.
Dennis came through the ranks at a club in his native city of Abuja before spending a season with Ukrainian club Zorya Luhansk.
He has emerged as an Arsenal target as boss Mikel Arteta eyes potential replacements with the situations of current forward pair Pierre-Emerick Aubameyang and Alexandre Lacazette far from certain.
Aubameyang is about to enter the final year of his deal and is yet to agree an extension at the Emirates Stadium.
The 30-year-old is a target for Real Madrid and Barcelona.