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Matteo Darmian and Antonio Valencia have been ruled out for a couple of weeks with what Ole Gunnar Solskjaer’s described on Friday as “niggles”, though Marcos Rojo has at least returned to training this week after his mystery injury – whether the Argentinean defender is match-fit is another matter, of course, after such a lengthy lay-off.
Anthony Martial will be pushing for a recall on the left flank at the expense of Alexis Sanchez, while Romelu Lukaku and Juan Mata come come into the reckoning in the attacking positions if Solskjaer decides to rotate – as he has done regularly since taking temporary charge at Old Trafford.
While Marcus Rashford is unlikely to be benched, the England forward could be redeployed out wide if his manager opts to include Lukaku in a central position.
The struggles of the much-maligned Belgian striker against Burnley in Gameweek 24, however, will be fresh in Solskjaer’s mind.
Andreas Pereira and Fred have been handed the odd start under the Norwegian head coach and could replace Ander Herrera at Craven Cottage, though neither back-up midfielder has particularly impressed in what little game-time they have been afforded.
Eric Bailly reclaimed his centre-back spot from Phil Jones at Leicester last weekend and could continue alongside the secure-looking Victor Lindelof, though the fit-again Chris Smalling is another name to add to the mix in that position.
Diogo Dalot gives Solskjaer the option of resting veteran Ashley Young at right-back, meanwhile.